Hotel Santo Domingo is located in Tuxtla Gutiérrez, 12 km from Sumidero Canyon and 3.2 km from Cana Hueca Park. The property is around 4.2 km from Victor Manuel Reyna Stadium, 4.3 km from Joyyo Mayu Park and 5.1 km from Chiapas Polyforum Convention Center. Free WiFi is available and private parking can be arranged at an extra charge.
At the hotel every room is fitted with a private bathroom.
Popular points of interest near Hotel Santo Domingo include San Marcos Cathedral, La Marimba Park and Botanical Garden Dr. Faustino Miranda. The nearest airport is Ángel Albino Corzo International Airport, 31 km from the accommodation.